Endocrine Abstracts

Estrogens play a protective role on the peripheral vascular endothelium in both females and males, however, no studies have reported on the effects of estrogens on male coronary arterial reactivity. We investigated the effects of estrogen therapy on coronary and endothelial function in a group of male to female transsexuals (M-to-F).Eight M-to-F transsexuals (group A), receiving oral estrogen therapy for 72 months were studied in comparison with 23 age-m...

GH deficiency (GHD) negatively influences cardiovascular function directly by impairing cardiac filling, performance, and contractility and indirectly by inducing atherosclerotic changes, hypercoagulability, abdominal obesity, insulin resistance, dislipidemia, endothelial dysfunction, etc. This accounts for the reduced life expectancy and increased risk of death for vascular disease in these patients.CFR represents the capacity of the coronary circulatio...